Many cancers are driven by hyperactive cell signaling proteins, known as kinases. Drugs that inhibit these kinases make attractive anticancer therapies. A bottleneck for kinase inhibitor development is being able to test whether inhibition is effective, for which current testing methods are inadequate. This method directly measures kinase activity in live cells, to better assess potential kinase inhibitors.
Cell-based test for kinase inhibitors
Simple, direct, cell-based test for kinase inhibitor development
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